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GBP | G Biological Products Blog
Proteomic Characterization of Venom from Scorpio fuscus: Insights for Therapeutic Applications
-This is the first proteomic profiling of Scorpio fuscus venom using gel-based decomplexation and LC-MS/MS.
-A total of 84 proteins were identified, including antimicrobial peptides with toxin-like characteristics.
-Identified venom proteins include phospholipases and ion channel inhibitors targeting calcium and potassium channels.
-UniProtKB annotation suggests 13 proteins are associated with lipid metabolism, with possible implications for angiogenesis.
hemocyanins and unid
Özgün Sipahioğlu
Sep 11, 20256 min read
Venom-Derived Peptides from Scorpions and Snakes as Emerging Therapeutics for Colorectal, Brain, and Uterine Cancers: Mechanisms, Species, and Translational Potential
Abstract Peptides extracted from scorpion and snake venom exhibit high specificity toward malignant cells due to their ability to bind to...
Özgün Sipahioğlu
May 4, 20254 min read
Mesobuthus eupeus venom modulates colorectal carcinoma signalingpathways and induces apoptosis
Colorectal cancer (CRC) is a significant global health concern, often challenging to treat effectively with conventional methods and burdened by adverse effects. Scorpion venoms offer a unique avenue for exploration, given their ability to disrupt the cell cycle, inhibit growth, and trigger apoptosis.
Özgün Sipahioğlu
Apr 15, 202526 min read
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